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Inhaler or spray, i started the Paxil and Chantix at the same time because my heart felt like it was not beating right and I was afraid I was having a heart attack. I have the most amazing and supportive friends and family, such as the Mayo Clinic, go cold turkey. I had been ready to quit my job and give up on everything. The FDA had logged 122 reports of suicides linked to Chantix, pfizer wants to assign full credit for the results from its five varenicline studies to Champix.

Believed to be the neuronal mechanism underlying reinforcement and reward experienced upon smoking. A few days went by and my craving for cigarettes returned.

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Probably the best week of my life and I went to bed with an overwhelming feeling of wanting to kill myself. I had never attempted suicide in my whole life before taking Chantix. I am tired all of the time.

I ended up in the mental unit at the hospital, was having severe panic attacks and suicidal thoughts. Chantix has had a devastating effect on my life. Although their accuracy and truthfulness cannot be verified, their numbers are far too many to ignore. He had not, had anything happen to him to which he would have had a reason for what occurred.

The nausea, stomach pain and constipation are so bad it’s been a chore to function. Those were mixed among the 26,000 reports of less-serious problems. It started about a week after starting the drug but I continued taking it thinking the symptoms would go away.

I tried Chantix for 3 weeks, and I woke up every morning after the first 2 weeks with the thought: why am I alive. My husband says that I have turned into one of those crazy chicks. I flipped between rage and suicidal depression so often and so rapidly, I was looking back at menopause as no big deal!

I thought I was going insane. 2 pill twice a day because of nausea and wicked dreams. I no longer have a personality.

It did however help through the withdrawal phase and could be useful but patients need to be informed of the possibility that they could experience this very harmful side effect. Extreme depression, anxiety, rage fits, suicidal thoughts constantly, it’s a miracle that I’m not in prison or 6 feet under right now.

Started Chantix and had great initial success I work as a counselor in a psychiatric hospital. So please tell my why I almost succeeded in killing myself and putting my husband of six years who does not smoke and three children through the worst three days of their lives. There’s a lot more to the story!

At this point it’s like I completely gave up. Overall, there were 1,055 reports of serious problems with Chantix reported in the third quarter of 2010, more than any other prescription medication regularly monitored by the drug safety agency, Mr Moore added. I was having dreams of things I would never even think about, things that have never crossed my mind. However, I slipped up and started smoking again at the beginning of week 3.

Please note that posts may be protected by a copyright notice appearing at the original posting site. Are nicotine weaning products a bad joke? I DO NOT RECOMMEND CHANTIX TO ANYONE! Be very careful with this drug.

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I was on Chantix for 6 months. Since taking this stuff I just want to give up. With absolutely no memory at all of what she’d done, Karen says her daughter’s account of what had happened was like hearing about another person. The comments below have been moderated in advance.

Lucky to still be here. I am so afraid for her. I was taken to the hospital for treatment and overnight observation. The withdrawals then were not near as bad as what I am going through right now.

I was angry, sad, disgusted and somewhat suicidal. I started taking Chantix in the beginning of Nov. After the 150 new Pfizer reports were added, the total jumped to 272. I’ve quit smoking before both on Zyban and with no medication whatsoever and NEVER had these side effects.

I am on an emotional rollarcoaster ride that seems to never end. For purposes of comparison, varenicline’s six-month rates were an identical 29.

It is nothing for me to lock myself in my bedroom and just cry. Did they smoke because they were depressed – or was their depression caused by Chantix? 2 years ago I quit cold turkey. NRT use during varenicline studies once the 12-week treatment period was complete.

I had nightmares, suicidal thoughts, didn’t care about anything and I thought smoking was better than these side effects. This is a very bad drug and should be pulled off the market. I tried to commit suicide December 8, 2007. I do feel a bit of nicotine craving but, will not smoke because I don’t want to have to feel like all of this craziness is for nothing.

I felt horrible all the time. What we do know is that Pfizer’s clinical Champix studies were not blind as claimed. FDA officials said the new reports did not change the agency’s position on the risks and benefits of the controversial drug, which received a black box warning that included suicide — the strongest caution possible — in 2009. At the time there was no knowledge of the drug’s dangers, but subsequently reports have come out.

BEFORE Chantix, I was the happiest person alive! If you take Chantix be very careful.

What else do you get her? We found Chantix in her nightstand with 4 doses gone. Chantix worked very well for me.

But, after taking Chantix 3 weeks I had nightmares, delusions, nervousness, and pain. I feel like I live in a fog all day. I was on Chantix for about 5 to 6 weeks. I began taking chantix on May 25, 07.

I have never had any emotional problems in my life and I am 52 After only a few days on Champix I attempted suicide and then 10 days later , repeated the attempt. This seems to unleash something in people. I think that Norman needed something from his brain chemistry to help him through a situational depressionsomething that Chantix had blocked.

People need to think about going on this drug, particularly if they have a history of depression. Thank God for this site. I felt as if no one cared about me and I just felt like crawling in a hole and dying. Which is so not normal.

Does the OTC Nicotine Patch Really Double Your Chances of Quitting? I used to be a very efficient multi tasker and nowI don’t know what the crap I am. That meant that the individual reports of injury were not logged in the FDA’s AERS system, drastically reducing known reports of suicides and other psychiatric problems tied to Chantix, Mr Moore said. If I could be certain that smoking would reverse what this drug has done to me I’d be smoking right now!

I took a pocket knife from my car, went into the woods and slit my wrists. The medicine was discontinued and the intense anxiety has decreased.

I have no recollection of the drive to and from work. I have had a big change in my personality, Im not the same persom anymore. Mooney warned researchers that, “to determine the prevalence of failure, clinical trials of NRT should uniformly test the integrity of study blinds. I’ve never had a period of aggressive behavior, I don’t drink alcohol or use drugs pretty much laid back and calm.

I know that it states that in rare cases suicide ideation can occur, but what is rare? Pfizer officials said they were submitting reports as required and that when the FDA asked them to change, they did so immediately. I have a feeling this stuff is going to hurt many people before it gets pulled from the market.

My boyfriend was depressed for 2 years but came out of it around 18 months ago. I went to one a day of the second week pack for about seven days and then stopped because I couldn’t sleep or focus.

I need help trying to help my sister get through this, as she found her husband when she came home for lunch. But he was normal in every other way.

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Thankfully, with this last hospitalization, my MD was aware of the recent reports of bad side effects from Chantix. I started cutting back to just one tablet a day. In the case of both NRT and varenicline, the expectations of withdrawal syndrome reduction were frustrated by assignment to the placebo group, or fulfilled by assignment to the active group, with the arrival of nicotine or varenicline in the brain. I wanted a kick start and spoke to my GP about Chantix.

My faimly talked me into quitting the chantix and i did. Agency officials said they are continuing to review Chantix in clinical trials. If so, the results have not yet been made public.

I miss and love all of them but i dont want to hurt them. I started taking Chantix 12 days ago.

I am a nurse administrator and well know the anticipated side effects of quitting smoking. He had horrific dreams, insomnia for days, and did not know what was real or unreal, if he was in reality or a dream, or nightmare. Champix and how much attributable to the 26 times in the Jorenby study that participants spent quality one-on-one time with their Champix provider, either in person or over the telephone?

I started Chantix in October. But these rates were achieved under highly artificial clinic study conditions. I ended up driving about 70 miles from my home. I tried to end my life but was saved by a co-worker.

Mr Moore, who has served as an expert witness in court cases related to Chantix, said it is the riskiest drug among those analysed from the FDA’s adverse event reports, msnbc. I am agitated and it’s very hard for me to focus. Varenicline blocks the ability of nicotine to activate a4b2 receptors and thus to stimulate the central nervous mesolimbic dopamine system, believed to be the neuronal mechanism underlying reinforcement and reward experienced upon smoking.

Federal Food and Drug Administration officials said that they asked Pfizer to resubmit thousands of records after realising that the company was sending required reports in an inappropriate format that could not be added to the agency’s Adverse Events Reporting System, or AERS. We won’t even begin to address my aggression and hostility issues. In Pfizer’s case, the firm was submitting the periodic reports as required, but combining summaries and individual case reports in a single text file, the FDA said.

This is no way to live! Mr Moore has asked the FDA to investigate the 150 new suicide reports, particularly if the events occurred before the 2009 black box warning listed suicide as a possible side effect. What possible explanation is there for the tremendous diversity in 12-week quitting rates among Champix users?

Just doesn’t make sense to me or my 2 daughters who miss their mom! 36 hours after my last dose. I thought I was going nuts! I do not have a history of either depression or suicidal thinking.

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They sought some degree of reduction in their withdrawal syndrome and none occurred. I am still trying to deal with the bouts of severe depression though. I had been ready to quit my job and give up on everything.

Anyone who ever mentions Chantix will be told by me to just quit cold turkey! I am usually not this way, but I scream and yell a lot.

I can”t ascertain whether what I did yesterday I actually did or I dreamt it! I’m growing at a record rate! I had overwhelming thoughts of suicide and just gave in to them.

Polito is solely responsible for the content of this article. Each author’s name and comment date is from the original full-text post. I just have to hope that these mental effects resolve soon.

Smokers join clinical studies in hopes of receiving promised medications that result in withdrawal symptom reduction. This was in June of 2007–prior to any warnings. The headaches are more like migraines.

It is now 1 week after stopping the Chantix. Who lives in a house like this?

Hoping to follow in her footsteps? By the grace of God someone saw my car in the field and called 911. 1 million times already this year.

My ex-wife committed suicide 4 days after starting Chantix. I have insomina and average about 3 hours of sleep a night.

I hated myself, then I felt sorry for myself. Father-of-two Wayne Marshall, 36, was found hanged shortly after completing a 13-week course of Champix Mr Marshall’s widow Emma said he was prescribed the drug by his GP last August to help him quit his 20-a-day habit, but quickly went downhill, cutting himself off from his family and friends.